How Does Leydig Cells Affect The Synthesis Of Testicular...

Successful testicular function depends on the hypothalamus discharge of GNRH, which in turn activates the release of LH and FSH to act on the testes and initiates the synthesis of testicular steroids. Active immunization dysfunction the hypothalamic-pituitary-gonad axis, thereby hindering the function of the Leydig and Sertoli cells and suppress the attainment of the testes maturity and steroid synthesis [Einarsson et al., 2009] and then lower the level testosterone hormones. The total serum testosterone concentrations are decreased, consistence with the treatment group research results obtained in a previous study [Ramzan et al., 2013]. Another previous study [Khan et al., 2008] showed that the serum testosterone levels are reduced in the†¦show more content†¦Furthermore, Huma et al., [2014] reported that protein 234 moderately lowered the testosterone response to KISS-1 gene. Thus reduction of testosterone in the bloodstream of the treatment group was achieved due to abnor mal function of the hypothalamus-pituitary-gonadal axis, implying that the kisspeptin recombinant oral vaccines participate in the disruption of testosterone secretion and the overcoming of ram sexual behaviors. The scale of the testicles is well correlated to the synthesis functionality of the sperm and further gonadal sperm reserves [Parkinson et al., 2004]. The scrotal circumference is the best and the most sophisticated device for estimating the mass of the reproductive organs [Lino et al., 1972; Notter et al., 1987] and the level of testes development [Lunstra et al., 1978] inside the animal. The testicle circumference and histological sections were assessed to determine the efficacy of the vaccine on gonadal features. Analysis of the sub-physiological contents of testicles revealed a direct relationship between the steroid and spermatogenic production. Our research finding shows that the vaccine has a strong effect on the scrotal circumference of immunized ram lambs compared with the control ram lambs (P 0.05). Furthermore, the microscopic histological outcomes of testicles indicate that the vaccinated ram lambs indicated lower masses of spermatogonium, spermatocytes, and spermatids. The histological observation revealed smaller seminiferousShow MoreRelatedWhat Are Androgenic Anabolic Steroids?1601 Words   |  7 PagesINTRODUCTION What are Androgenic-Anabolic Steroids? Androgenic-anabolic steroids (AAS) are synthetic derivatives of the male hormone testosterone. Testosterone is produced in the Leydig cells of the testes. Scientist have tried to reproduce a synthetic form of this hormone since the early 1900s. As early as 1935, the production of synthetic hormones has been possible. These hormones have two distinct effects. The androgenic effects which produce the development of the male characteristics such